The global neurological biomarkers market was valued at USD 8.10 Billion in 2023 and is anticipated to grow at a CAGR of 11.8% from 2024 to 2033. Neurological biomarkers play a crucial role in diagnosing various diseases, including autism, Parkinson's disease, and depression. They encompass metabolomics as well as imaging-based, genomic-based, and proteomic-based markers. These biomarkers can be categorized into four major types: metabolomics, imaging technologies, genomics studies, and proteomics analyses. Utilizing these biomarkers enhances the treatment efficacy for neurological disorders by expediting drug development processes while enabling earlier diagnoses through non-invasive methods. Additionally, digital biomarkers provide pharmaceutical companies with significant insights that support better decision-making during clinical trials—further driving growth within the neurological biomarker market.
A neurological biomarker refers to any biological substance or characteristic that can be objectively measured and assessed as an indicator of normal or diseased states within the nervous system. These biomarkers are valuable for evaluating the risk of developing neurological conditions, monitoring disease progression, assessing treatment impacts, and predicting patient outcomes. Their utility covers diagnostic, prognostic, and predictive areas, each vital in managing neurological disorders. Neurological biomarkers are measurable indicators that provide insights into neurological processes, disease states, or treatment responses. These biomarkers can aid in diagnosing, monitoring, and predicting outcomes for various neurological conditions. In biological samples like blood and cerebrospinal fluid (CSF) and through imaging data, they offer a glimpse into the brain's functional mechanisms and disorders. Recently, these biomarkers have attracted considerable interest due to their potential impact on neurology by facilitating earlier detection of diseases such as Alzheimer's and Parkinson's disease, improving patient stratification, and enabling more personalized treatment procedures for multiple sclerosis and stroke, among other conditions.
Get an overview of this study by requesting a free sample
Rising Prevalence of Neurological Disorders - A key factor propelling the global neurological biomarkers market is the rising incidence of neurological disorders worldwide. Diseases such as Alzheimer's, Parkinson's, multiple sclerosis, and epilepsy are increasingly prevalent, particularly among elderly populations. As the number of people over 65 years old is anticipated to increase significantly in the coming decades, so too will those affected by neurodegenerative and age-related brain diseases. The World Health Organization (WHO) reports that about a billion individuals currently suffer from neurological conditions globally—with Alzheimer's and other dementias ranking high among causes of disability and mortality in older adults. This growing prevalence fosters demand for neurological biomarkers crucial for early diagnosis and effective management tools for these ailments—thereby driving market growth. This factor is stimulating the market growth and development.
High Manufacturing Costs – The development and validation of neurological biomarkers are both lengthy and expensive trials. This process demands identifying potential biomarkers and confirming their validity through extensive preclinical and clinical testing, a journey that can span several years and necessitates significant financial investment. Expenses rise even further when specialized assays or cutting-edge technologies like genomics, proteomics, or imaging are involved. Moreover, the development phase often requires multiple optimization cycles to guarantee accuracy, sensitivity, and specificity—factors that drive up costs. These substantial financial requirements restrict the number of organizations capable of engaging in biomarker research and development activities, ultimately slowing market expansion. This factor is limiting the market growth.
Growing Awareness and Early Diagnosis Initiatives - Awareness campaigns and early diagnosis efforts by healthcare organizations and patient advocacy groups have been pivotal in advancing the neurological biomarkers market. As familiarity with neurological diseases expands, there is a growing demand for diagnostic tools that support early intervention. This aspect is especially important for neurodegenerative conditions like Alzheimer's and Parkinson's, where treatments are most effective when administered at an early stage of the disease. Organizations such as the Alzheimer's Association and Parkinson's Foundation actively encourage early screening and diagnosis, boosting demand for biomarkers capable of detecting these diseases before major symptoms develop. Thus, public awareness initiatives combined with a focus on early diagnosis have created a supportive environment for growth in the neurological biomarker sector. This factor is anticipated to provide lucrative growth opportunities in the upcoming years.
The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America region emerged as the most prominent Neurological biomarkers market, with a 38.0% market revenue share in 2023. The U.S. country hosts numerous prominent biotechnology and pharmaceutical firms that focus extensively on biomarker research, especially in the fields of Alzheimer's disease, Parkinson's disease, and multiple sclerosis. This effort is supported by private sector investments and government organizations/associations like the National Institutes of Health (NIH), ensuring a steady flow of resources toward neurological biomarker development. The NIH allocates billions each year to neurological research projects, including initiatives for discovering biomarkers to enhance diagnosis and treatment options. These substantial investments greatly enhance North America's ability to innovate new biomarkers and bring them to market, strengthening its global competitive position. The regional market players also engage in various market strategies such as product innovation, product differentiation, mergers, acquisitions, partnerships, and strategic alliances to maintain their competitive edge.
North America Region Neurological Biomarkers Market Share in 2023 - 38.0%
www.thebrainyinsights.com
Check the geographical analysis of this market by requesting a free sample
The type segment includes genomics biomarkers, proteomics biomarkers, metabolomics biomarkers, imaging biomarkers and others. The proteomics biomarkers segment dominated, with a market share of around 38% in 2023. Numerous advanced systems can detect and measure low concentrations of proteomic neurological biomarkers. For instance, Merck's SMCxPRO technology can quantify proteins in blood plasma samples, aiding the management of neurological disorders like Alzheimer's disease. This capability has facilitated early diagnosis of such conditions, driving market expansion. Furthermore, recent enhancements in instrument sensitivity and reproducibility—including LC-MS/MS technologies, microarray advancements, and breakthroughs in immunoassay-based single-molecule quantification and multiplexing—are significantly advancing research into proteomics-based biomarkers.
The end-user segment includes hospital laboratories, independent clinical diagnostic centers and research organizations. The research organizations segment dominated, with a market share of around 42% in 2023. Research institutions like the National Institute of Neurological Disorders and Stroke (NINDS) have offered substantial funding for discovering, validating, and qualifying biomarkers related to various neurological disorders. In May 2022, Amprion Inc. was awarded an additional research grant from NINDS, totaling approximately USD 730,000, to further validate its SYNTap Biomarker Test aimed at diagnosing neurological diseases or disorders.
The application segment includes Alzheimer’s Disease, Parkinson’s Disease, Multiple Sclerosis and others. The Alzheimer’s Disease segment dominated, with a market share of around 37% in 2023. The rising incidence of Alzheimer's disease, coupled with increased clinical trials and research focused on AD drug development, is contributing to the segment's growth. Biomarkers play a crucial role in diagnosing the condition by indicating target engagement, supporting efforts for disease modification, and ensuring safety through testing. The rapid expansion of the elderly population—who are at greater risk for Alzheimer's—further drives market growth. According to the Alzheimer's Association, nearly 55 million people worldwide currently have dementia—a figure projected to rise to 77 million by 2030 and approximately 138 million by 2050. In addition, an estimated 7 million individuals in the U.S. live with Alzheimer's disease.
Report Description:
Attribute | Description |
---|---|
Market Size | Revenue (USD Billion) |
Market size value in 2023 | USD 8.10 Billion |
Market size value in 2033 | USD 24.71 Billion |
CAGR (2024 to 2033) | 11.8% |
Historical data | 2020-2022 |
Base Year | 2023 |
Forecast | 2024-2033 |
Region | The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East & Africa. Furthermore, the regions are further analyzed at the country level. |
Segments | Type, Application, End-user |
As per The Brainy Insights, the size of the global neurological biomarkers market was valued at USD 8.10 billion in 2023 to USD 24.71 billion by 2033.
The global neurological biomarkers market is growing at a CAGR of 11.8% during the forecast period 2024-2033.
North America region became the largest market for neurological biomarkers.
The rising prevalence of neurological disorders in developed and developing countries is driving the market's growth.
This study forecasts revenue at global, regional, and country levels from 2020 to 2033. The Brainy Insights has segmented the global neurological biomarkers market based on below-mentioned segments:
Global Neurological Biomarkers Market by Type:
Global Neurological Biomarkers Market by End-user:
Global Neurological Biomarkers Market by Application:
Global Neurological Biomarkers Market by Region:
Research has its special purpose to undertake marketing efficiently. In this competitive scenario, businesses need information across all industry verticals; the information about customer wants, market demand, competition, industry trends, distribution channels etc. This information needs to be updated regularly because businesses operate in a dynamic environment. Our organization, The Brainy Insights incorporates scientific and systematic research procedures in order to get proper market insights and industry analysis for overall business success. The analysis consists of studying the market from a miniscule level wherein we implement statistical tools which helps us in examining the data with accuracy and precision.
Our research reports feature both; quantitative and qualitative aspects for any market. Qualitative information for any market research process are fundamental because they reveal the customer needs and wants, usage and consumption for any product/service related to a specific industry. This in turn aids the marketers/investors in knowing certain perceptions of the customers. Qualitative research can enlighten about the different product concepts and designs along with unique service offering that in turn, helps define marketing problems and generate opportunities. On the other hand, quantitative research engages with the data collection process through interviews, e-mail interactions, surveys and pilot studies. Quantitative aspects for the market research are useful to validate the hypotheses generated during qualitative research method, explore empirical patterns in the data with the help of statistical tools, and finally make the market estimations.
The Brainy Insights offers comprehensive research and analysis, based on a wide assortment of factual insights gained through interviews with CXOs and global experts and secondary data from reliable sources. Our analysts and industry specialist assume vital roles in building up statistical tools and analysis models, which are used to analyse the data and arrive at accurate insights with exceedingly informative research discoveries. The data provided by our organization have proven precious to a diverse range of companies, facilitating them to address issues such as determining which products/services are the most appealing, whether or not customers use the product in the manner anticipated, the purchasing intentions of the market and many others.
Our research methodology encompasses an idyllic combination of primary and secondary initiatives. Key phases involved in this process are listed below:
The phase involves the gathering and collecting of market data and its related information with the help of different sources & research procedures.
The data procurement stage involves in data gathering and collecting through various data sources.
This stage involves in extensive research. These data sources includes:
Purchased Database: Purchased databases play a crucial role in estimating the market sizes irrespective of the domain. Our purchased database includes:
Primary Research: The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. Primary research mainly involves in telephonic interviews, E-mail interactions and face-to-face interviews with the raw material providers, manufacturers/producers, distributors, & independent consultants. The interviews that we conduct provides valuable data on market size and industry growth trends prevailing in the market. Our organization also conducts surveys with the various industry experts in order to gain overall insights of the industry/market. For instance, in healthcare industry we conduct surveys with the pharmacists, doctors, surgeons and nurses in order to gain insights and key information of a medical product/device/equipment which the customers are going to usage. Surveys are conducted in the form of questionnaire designed by our own analyst team. Surveys plays an important role in primary research because surveys helps us to identify the key target audiences of the market. Additionally, surveys helps to identify the key target audience engaged with the market. Our survey team conducts the survey by targeting the key audience, thus gaining insights from them. Based on the perspectives of the customers, this information is utilized to formulate market strategies. Moreover, market surveys helps us to understand the current competitive situation of the industry. To be precise, our survey process typically involve with the 360 analysis of the market. This analytical process begins by identifying the prospective customers for a product or service related to the market/industry to obtain data on how a product/service could fit into customers’ lives.
Secondary Research: The secondary data sources includes information published by the on-profit organizations such as World bank, WHO, company fillings, investor presentations, annual reports, national government documents, statistical databases, blogs, articles, white papers and others. From the annual report, we analyse a company’s revenue to understand the key segment and market share of that organization in a particular region. We analyse the company websites and adopt the product mapping technique which is important for deriving the segment revenue. In the product mapping method, we select and categorize the products offered by the companies catering to domain specific market, deduce the product revenue for each of the companies so as to get overall estimation of the market size. We also source data and analyses trends based on information received from supply side and demand side intermediaries in the value chain. The supply side denotes the data gathered from supplier, distributor, wholesaler and the demand side illustrates the data gathered from the end customers for respective market domain.
The supply side for a domain specific market is analysed by:
The demand side for the market is estimated through:
In-house Library: Apart from these third-party sources, we have our in-house library of qualitative and quantitative information. Our in-house database includes market data for various industry and domains. These data are updated on regular basis as per the changing market scenario. Our library includes, historic databases, internal audit reports and archives.
Sometimes there are instances where there is no metadata or raw data available for any domain specific market. For those cases, we use our expertise to forecast and estimate the market size in order to generate comprehensive data sets. Our analyst team adopt a robust research technique in order to produce the estimates:
Data Synthesis: This stage involves the analysis & mapping of all the information obtained from the previous step. It also involves in scrutinizing the data for any discrepancy observed while data gathering related to the market. The data is collected with consideration to the heterogeneity of sources. Robust scientific techniques are in place for synthesizing disparate data sets and provide the essential contextual information that can orient market strategies. The Brainy Insights has extensive experience in data synthesis where the data passes through various stages:
Market Deduction & Formulation: The final stage comprises of assigning data points at appropriate market spaces so as to deduce feasible conclusions. Analyst perspective & subject matter expert based holistic form of market sizing coupled with industry analysis also plays a crucial role in this stage.
This stage involves in finalization of the market size and numbers that we have collected from data integration step. With data interpolation, it is made sure that there is no gap in the market data. Successful trend analysis is done by our analysts using extrapolation techniques, which provide the best possible forecasts for the market.
Data Validation & Market Feedback: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helps us finalize data-points to be used for final calculations.
The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. The data validation interview and discussion panels are typically composed of the most experienced industry members. The participants include, however, are not limited to:
Moreover, we always validate our data and findings through primary respondents from all the major regions we are working on.
Free Customization
Fortune 500 Clients
Free Yearly Update On Purchase Of Multi/Corporate License
Companies Served Till Date