The global neurological biomarkers market was valued at USD 8.10 Billion in 2023 and is anticipated to grow at a CAGR of 11.8% from 2024 to 2033. Neurological biomarkers play a crucial role in diagnosing various diseases, including autism, Parkinson's disease, and depression. They encompass metabolomics as well as imaging-based, genomic-based, and proteomic-based markers. These biomarkers can be categorized into four major types: metabolomics, imaging technologies, genomics studies, and proteomics analyses. Utilizing these biomarkers enhances the treatment efficacy for neurological disorders by expediting drug development processes while enabling earlier diagnoses through non-invasive methods. Additionally, digital biomarkers provide pharmaceutical companies with significant insights that support better decision-making during clinical trials—further driving growth within the neurological biomarker market.
A neurological biomarker refers to any biological substance or characteristic that can be objectively measured and assessed as an indicator of normal or diseased states within the nervous system. These biomarkers are valuable for evaluating the risk of developing neurological conditions, monitoring disease progression, assessing treatment impacts, and predicting patient outcomes. Their utility covers diagnostic, prognostic, and predictive areas, each vital in managing neurological disorders. Neurological biomarkers are measurable indicators that provide insights into neurological processes, disease states, or treatment responses. These biomarkers can aid in diagnosing, monitoring, and predicting outcomes for various neurological conditions. In biological samples like blood and cerebrospinal fluid (CSF) and through imaging data, they offer a glimpse into the brain's functional mechanisms and disorders. Recently, these biomarkers have attracted considerable interest due to their potential impact on neurology by facilitating earlier detection of diseases such as Alzheimer's and Parkinson's disease, improving patient stratification, and enabling more personalized treatment procedures for multiple sclerosis and stroke, among other conditions.
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Rising Prevalence of Neurological Disorders - A key factor propelling the global neurological biomarkers market is the rising incidence of neurological disorders worldwide. Diseases such as Alzheimer's, Parkinson's, multiple sclerosis, and epilepsy are increasingly prevalent, particularly among elderly populations. As the number of people over 65 years old is anticipated to increase significantly in the coming decades, so too will those affected by neurodegenerative and age-related brain diseases. The World Health Organization (WHO) reports that about a billion individuals currently suffer from neurological conditions globally—with Alzheimer's and other dementias ranking high among causes of disability and mortality in older adults. This growing prevalence fosters demand for neurological biomarkers crucial for early diagnosis and effective management tools for these ailments—thereby driving market growth. This factor is stimulating the market growth and development.
High Manufacturing Costs – The development and validation of neurological biomarkers are both lengthy and expensive trials. This process demands identifying potential biomarkers and confirming their validity through extensive preclinical and clinical testing, a journey that can span several years and necessitates significant financial investment. Expenses rise even further when specialized assays or cutting-edge technologies like genomics, proteomics, or imaging are involved. Moreover, the development phase often requires multiple optimization cycles to guarantee accuracy, sensitivity, and specificity—factors that drive up costs. These substantial financial requirements restrict the number of organizations capable of engaging in biomarker research and development activities, ultimately slowing market expansion. This factor is limiting the market growth.
Growing Awareness and Early Diagnosis Initiatives - Awareness campaigns and early diagnosis efforts by healthcare organizations and patient advocacy groups have been pivotal in advancing the neurological biomarkers market. As familiarity with neurological diseases expands, there is a growing demand for diagnostic tools that support early intervention. This aspect is especially important for neurodegenerative conditions like Alzheimer's and Parkinson's, where treatments are most effective when administered at an early stage of the disease. Organizations such as the Alzheimer's Association and Parkinson's Foundation actively encourage early screening and diagnosis, boosting demand for biomarkers capable of detecting these diseases before major symptoms develop. Thus, public awareness initiatives combined with a focus on early diagnosis have created a supportive environment for growth in the neurological biomarker sector. This factor is anticipated to provide lucrative growth opportunities in the upcoming years.
The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America region emerged as the most prominent Neurological biomarkers market, with a 38.0% market revenue share in 2023. The U.S. country hosts numerous prominent biotechnology and pharmaceutical firms that focus extensively on biomarker research, especially in the fields of Alzheimer's disease, Parkinson's disease, and multiple sclerosis. This effort is supported by private sector investments and government organizations/associations like the National Institutes of Health (NIH), ensuring a steady flow of resources toward neurological biomarker development. The NIH allocates billions each year to neurological research projects, including initiatives for discovering biomarkers to enhance diagnosis and treatment options. These substantial investments greatly enhance North America's ability to innovate new biomarkers and bring them to market, strengthening its global competitive position. The regional market players also engage in various market strategies such as product innovation, product differentiation, mergers, acquisitions, partnerships, and strategic alliances to maintain their competitive edge.
North America Region Neurological Biomarkers Market Share in 2023 - 38.0%
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The type segment includes genomics biomarkers, proteomics biomarkers, metabolomics biomarkers, imaging biomarkers and others. The proteomics biomarkers segment dominated, with a market share of around 38% in 2023. Numerous advanced systems can detect and measure low concentrations of proteomic neurological biomarkers. For instance, Merck's SMCxPRO technology can quantify proteins in blood plasma samples, aiding the management of neurological disorders like Alzheimer's disease. This capability has facilitated early diagnosis of such conditions, driving market expansion. Furthermore, recent enhancements in instrument sensitivity and reproducibility—including LC-MS/MS technologies, microarray advancements, and breakthroughs in immunoassay-based single-molecule quantification and multiplexing—are significantly advancing research into proteomics-based biomarkers.
The end-user segment includes hospital laboratories, independent clinical diagnostic centers and research organizations. The research organizations segment dominated, with a market share of around 42% in 2023. Research institutions like the National Institute of Neurological Disorders and Stroke (NINDS) have offered substantial funding for discovering, validating, and qualifying biomarkers related to various neurological disorders. In May 2022, Amprion Inc. was awarded an additional research grant from NINDS, totaling approximately USD 730,000, to further validate its SYNTap Biomarker Test aimed at diagnosing neurological diseases or disorders.
The application segment includes Alzheimer’s Disease, Parkinson’s Disease, Multiple Sclerosis and others. The Alzheimer’s Disease segment dominated, with a market share of around 37% in 2023. The rising incidence of Alzheimer's disease, coupled with increased clinical trials and research focused on AD drug development, is contributing to the segment's growth. Biomarkers play a crucial role in diagnosing the condition by indicating target engagement, supporting efforts for disease modification, and ensuring safety through testing. The rapid expansion of the elderly population—who are at greater risk for Alzheimer's—further drives market growth. According to the Alzheimer's Association, nearly 55 million people worldwide currently have dementia—a figure projected to rise to 77 million by 2030 and approximately 138 million by 2050. In addition, an estimated 7 million individuals in the U.S. live with Alzheimer's disease.
Attribute | Description |
---|---|
Market Size | Revenue (USD Billion) |
Market size value in 2023 | USD 8.10 Billion |
Market size value in 2033 | USD 24.71 Billion |
CAGR (2024 to 2033) | 11.8% |
Historical data | 2020-2022 |
Base Year | 2023 |
Forecast | 2024-2033 |
Region | The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East & Africa. Furthermore, the regions are further analyzed at the country level. |
Segments | Type, Application, End-user |
As per The Brainy Insights, the size of the global neurological biomarkers market was valued at USD 8.10 billion in 2023 to USD 24.71 billion by 2033.
The global neurological biomarkers market is growing at a CAGR of 11.8% during the forecast period 2024-2033.
North America region became the largest market for neurological biomarkers.
The rising prevalence of neurological disorders in developed and developing countries is driving the market's growth.
This study forecasts revenue at global, regional, and country levels from 2020 to 2033. The Brainy Insights has segmented the global neurological biomarkers market based on below-mentioned segments:
Global Neurological Biomarkers Market by Type:
Global Neurological Biomarkers Market by End-user:
Global Neurological Biomarkers Market by Application:
Global Neurological Biomarkers Market by Region:
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