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The global Myelofibrosis (MF) Treatment market was valued at USD 847.1 million in 2023 and growing at a CAGR of 4.20% from 2023 to 2031. The market is expected to reach USD 1177.2 million by 2031. The rise in awareness about Myelofibrosis (MF) Treatment and the peak in the number of patients are also expected to boost the number of products mainly related to the disease produced in the forecast years. Similarly, the reimbursement policy related to multiple patent expirations, the market for Myelofibrosis (MF) Treatment is anticipated to grow at an average pace throughout the prediction period.
Myelofibrosis is a rare blood cancer where scar tissue builds in the bone marrow. It’s a type of chronic leukemia that affects too many irregular blood cells being made. Finally, these cells can substitute normal cells. Treatment goals primarily involve managing symptoms and conditions that arise, including anemia and an enlarged spleen. Myelofibrosis is related to a genetic mutation in blood stem cells. Regardless, researchers aren’t sure what causes the transformation. When the mutated cells repeat and divide, they pass the mutation on to new blood cells. Ultimately, the mutated cells overtake the bone marrow’s ability to make healthy blood cells. Which usually results in too few red blood cells and too many white blood cells. It also generates scarring and hardening of the bone marrow, which is generally soft and spongy. Myelofibrosis usually shows up on a routine complete blood count (CBC). People with MF tend to have deficient red blood cells, unusually high or low white blood cells (WBCs), and platelets. Based on the CBC test, the doctor might also do a bone marrow biopsy, which involves taking a small sample of the bone marrow and looking at it more closely for signs of myelofibrosis, like scarring. The MF treatments include Stem cell transplants that have the potential to cure MF and repair bone marrow function. The process can cause life-threatening complications, so it’s usually only done when nothing else works. Myelofibrosis usually doesn’t provoke symptoms in its earlier stages; it can ultimately lead to severe complications, including more aggressive types of cancer. Living with Myelofibrosis can be stressful, so it might be helpful to seek support from organizations like the Myeloproliferative Neoplasm Research Foundation and Leukemia and Lymphoma Society. There are two types of myelofibrosis first is Primary myelofibrosis, which occurs on its own. And another is secondary myelofibrosis appears secondary to other blood disorders, including primary thrombocytosis or polycythemia vera. Secondary myelofibrosis accounts for about 10% to 20% of diagnoses.
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In June 2022, AbbVie declared new findings from Cohort 3 of its Phase 2 REFINE study of investigational navitoclax in combination with ruxolitinib in JAK inhibitor-naive patients with myelofibrosis (MF), a rare and difficult-to-treat blood cancer. Navitoclax is now under Phase III clinical trials.
In May 2020, Geron Corporation, a late-stage clinical biopharmaceutical company, revealed strategies for a Phase 3 clinical trial in Myelofibrosis patients who have failed from treatment with a Janus kinase (JAK) inhibitor, including trial design and expected trial start and data readout timelines.
In June 2022, Sierra Oncology conducted Phase III data in ASCO 2022 and at the European Hematology Association Hybrid Congress 2022. Based on the affirmative results, the company submitted an NDA to FDA in the second quarter of 2022.
Increased Awareness related To Chemotherapy- Chemotherapy is a systemic drug that travels through the bloodstream and runs all body parts. There are numerous different types of Chemotherapy. In general, medications used for Chemotherapy are powerful chemicals that treat cancer by attacking cells during distinct parts of the cell cycle. All cells go through the cell cycle, which is how new cells are made. Cancer cells go through this procedure more quickly than normal cells, so Chemotherapy impacts these fast-growing cells better due to Chemotherapy travels via the whole body; it can also damage healthy cells as they go through their normal cell cycle. That is the reason chemotherapy can cause side effects like nausea and hair loss.
Uncertainty in Diagnosis of Myelofibrosis Symptoms Hampers the Growth of the Patient- Genetic transformations in stem cells in the bone marrow push myelofibrosis. A prevalence of people with the disorder are over 50 and don't exhibit any signs earlier. It will hamper the growth of the market. The worldwide market is not showing any revenue growth due to the need for more understanding regarding myelofibrosis disease and the high prices related to treatment. Similarly, the side effects of myelofibrosis treatment drugs are anticipated to drain market growth shortly.
Advancement In New Therapies Obtained a Major Growth- Due to the increasing majority of different genetic disorders and the changing in lifestyle pattern, the myelofibrosis treatment market is predicted to grow due to advancement in new therapies. Myelofibrosis treatment market revenue development is expected to be pushed by the increased number of smokers worldwide, supporting revenue development. Further, government investments are anticipated to grow in the healthcare infrastructure, particularly in developing countries, which is predicted to promote revenue growth.
The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America emerged as the largest market for the global Myelofibrosis (MF) Treatment market, with a 38.5% share of the market revenue in 2023.
Owning a well-established healthcare system and an increased awareness of cancer patients, North America is expected to hold the maximum share of the global healthcare market in 2023. The region is undergoing substantial growth owing to one of the fastest-growing diseases in the world, improved awareness about its manifestations, and proper reimbursement conditions corresponding with other economies.
North America Region Myelofibrosis (MF) Treatment Market Share in 2023 - 38.5%
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The type segment is divided into chemotherapy, targeted therapy, and others. The chemotherapy segment dominated the market, with a market share of around 35% in 2023. Chemotherapy drug market growth is anticipated to be increased by growing cancer prevalence. Development in healthcare expenses also pushes the growth of the chemotherapy market. Governments are also trying to improve the healthcare infrastructure by raising government funds available to the industry, which will further influence the market.
The route of administration segment is divided into parenteral, oral, and others. The oral segment dominated the market, with a market share of around 38% in 2023. Drug routes for treating cancer have driven great understanding and adaption in the market. The FDA newly approved the first drug, especially for patients with severely low platelet counts (thrombocytopenia), in managing myelofibrosis with intermediate or high-risk thrombocytopenia.
The end-use segment is divided into homecare, hospitals, retail pharmacy, specialty clinics, and others. The retail pharmacy segment dominated the market, with a market share of around 25% in 2023. The retail pharmacy companies segment held the highest share in the market due to the advanced investments in research & development to establish beneficial drug treatments for treating severe diseases like myelofibrosis
Report Description:
| Attribute | Description |
|---|---|
| Market Size | Revenue (USD Million) |
| Market size value in 2023 | USD 847.1 Million |
| Market size value in 2031 | USD 1177.2 Million |
| CAGR (2023 to 2031) | 4.20% |
| Historical data | 2019-2021 |
| Base Year | 2022 |
| Forecast | 2023-2031 |
| Regional Segments | The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East & Africa. Furthermore, the regions are further analyzed at the country level. |
| Segments | Type, Route of Administration, End-Use |
As per The Brainy Insights, the size of the Myelofibrosis (MF) Treatment market was valued at USD 847.1 million in 2023 to USD 1177.2 million by 2031.
Global Myelofibrosis (MF) Treatment market is growing at a CAGR of 4.20% during the forecast period 2023-2031.
North America region emerged as the largest market for the Myelofibrosis (MF) Treatment market.
1. Introduction
1.1. Objectives of the Study
1.2. Market Definition
1.3. Research Scope
1.4. Currency
1.5. Key Target Audience
2. Research Methodology and Assumptions
3. Executive Summary
4. Premium Insights
4.1. Porter’s Five Forces Analysis
4.2. Value Chain Analysis
4.3. Top Investment Pockets
4.3.1. Market Attractiveness Analysis by Type
4.3.2. Market Attractiveness Analysis by Route of Administration
4.3.3. Market Attractiveness Analysis by End-Use
4.3.4. Market Attractiveness Analysis by Region
4.4. Industry Trends
5. Market Dynamics
5.1. Market Evaluation
5.2. Drivers
5.2.1. Increased awareness related to chemotherapy
5.3. Restraints
5.3.1. Uncertainty in diagnosis of myelofibrosis symptoms hampers the growth of the patient
5.4. Opportunities
5.4.1. Advancement in new therapies obtained a major growth
6. Global Myelofibrosis (MF) Treatment Market Analysis and Forecast, By Type:
6.1. Segment Overview
6.2. Chemotherapy
6.3. Targeted Therapy
6.4. Others
7. Global Myelofibrosis (MF) Treatment Market Analysis and Forecast, By Route of Administration
7.1. Segment Overview
7.2. Parenteral
7.3. Oral
7.4. Others
8. Global Myelofibrosis (MF) Treatment Market Analysis and Forecast, By End-Use
8.1. Segment Overview
8.2. Homecare
8.3. Hospitals
8.4. Retail Pharmacy
8.5. Specialty Clinics
8.6. Others
9. Global Myelofibrosis (MF) Treatment Market Analysis and Forecast, By Regional Analysis
9.1. Segment Overview
9.2. North America
9.2.1. U.S.
9.2.2. Canada
9.2.3. Mexico
9.3. Europe
9.3.1. Germany
9.3.2. France
9.3.3. U.K.
9.3.4. Italy
9.3.5. Spain
9.4. Asia-Pacific
9.4.1. Japan
9.4.2. China
9.4.3. India
9.5. South America
9.5.1. Brazil
9.6. Middle East and Africa
9.6.1. UAE
9.6.2. South Africa
10. Global Myelofibrosis (MF) Treatment Market-Competitive Landscape
10.1. Overview
10.2. Market Share of Key Players in the Myelofibrosis (MF) Treatment Market
10.2.1. Global Company Market Share
10.2.2. North America Company Market Share
10.2.3. Europe Company Market Share
10.2.4. APAC Company Market Share
10.3. Competitive Situations and Trends
10.3.1. Product Launches and Developments
10.3.2. Partnerships, Collaborations, and Agreements
10.3.3. Mergers & Acquisitions
10.3.4. Expansions
11. Company Profiles
11.1. Teva Pharmaceutical Industries Ltd.
11.1.1. Business Overview
11.1.2. Company Snapshot
11.1.3. Company Market Share Analysis
11.1.4. Company Product Portfolio
11.1.5. Recent Developments
11.1.6. SWOT Analysis
11.2. Sun Pharmaceutical Industries Ltd.
11.2.1. Business Overview
11.2.2. Company Snapshot
11.2.3. Company Market Share Analysis
11.2.4. Company Product Portfolio
11.2.5. Recent Developments
11.2.6. SWOT Analysis
11.3. Sanofi
11.3.1. Business Overview
11.3.2. Company Snapshot
11.3.3. Company Market Share Analysis
11.3.4. Company Product Portfolio
11.3.5. Recent Developments
11.3.6. SWOT Analysis
11.4. Pfizer Inc
11.4.1. Business Overview
11.4.2. Company Snapshot
11.4.3. Company Market Share Analysis
11.4.4. Company Product Portfolio
11.4.5. Recent Developments
11.4.6. SWOT Analysis
11.5. Novartis AG
11.5.1. Business Overview
11.5.2. Company Snapshot
11.5.3. Company Market Share Analysis
11.5.4. Company Product Portfolio
11.5.5. Recent Developments
11.5.6. SWOT Analysis
11.6. Mylan N.V.
11.6.1. Business Overview
11.6.2. Company Snapshot
11.6.3. Company Market Share Analysis
11.6.4. Company Product Portfolio
11.6.5. Recent Developments
11.6.6. SWOT Analysis
11.7. Hikma Pharmaceuticals PLC
11.7.1. Business Overview
11.7.2. Company Snapshot
11.7.3. Company Market Share Analysis
11.7.4. Company Product Portfolio
11.7.5. Recent Developments
11.7.6. SWOT Analysis
11.8. GSK Plc.
11.8.1. Business Overview
11.8.2. Company Snapshot
11.8.3. Company Market Share Analysis
11.8.4. Company Product Portfolio
11.8.5. Recent Developments
11.8.6. SWOT Analysis
11.9. F. Hoffmann-La Roche Ltd
11.9.1. Business Overview
11.9.2. Company Snapshot
11.9.3. Company Market Share Analysis
11.9.4. Company Product Portfolio
11.9.5. Recent Developments
11.9.6. SWOT Analysis
11.10. Bristol Myers Squibb Company.
11.10.1. Business Overview
11.10.2. Company Snapshot
11.10.3. Company Market Share Analysis
11.10.4. Company Product Portfolio
11.10.5. Recent Developments
11.10.6. SWOT Analysis
11.11. Boehringer Ingelheim International Gmbh.
11.11.1. Business Overview
11.11.2. Company Snapshot
11.11.3. Company Market Share Analysis
11.11.4. Company Product Portfolio
11.11.5. Recent Developments
11.11.6. SWOT Analysis
11.12. Bayer AG.
11.12.1. Business Overview
11.12.2. Company Snapshot
11.12.3. Company Market Share Analysis
11.12.4. Company Product Portfolio
11.12.5. Recent Developments
11.12.6. SWOT Analysis
List of Table
1. Global Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
2. Global Chemotherapy Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
3. Global Targeted Therapy Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
4. Global Others Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
5. Global Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
6. Global Parenteral Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
7. Global Oral Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
8. Global Others Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
9. Global Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
10. Global Homecare Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
11. Global Hospitals Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
12. Global Retail Pharmacy Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
13. Global Specialty Clinics Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
14. Global Others Myelofibrosis (MF) Treatment Market, By Region, 2019-2031 (USD Million)
15. North America Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
16. North America Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
17. North America Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
18. U.S. Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
19. U.S. Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
20. U.S. Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
21. Canada Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
22. Canada Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
23. Canada Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
24. Mexico Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
25. Mexico Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
26. Mexico Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
27. Europe Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
28. Europe Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
29. Europe Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
30. Germany Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
31. Germany Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
32. Germany Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
33. France Myelofibrosis (MF) Treatment Market, By Type 2019-2031 (USD Million)
34. France Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
35. France Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
36. U.K. Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
37. U.K. Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
38. U.K. Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
39. Italy Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
40. Italy Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
41. Italy Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
42. Spain Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
43. Spain Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
44. Spain Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
45. Asia Pacific Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
46. Asia Pacific Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
47. Asia Pacific Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
48. Japan Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
49. Japan Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
50. Japan Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
51. China Myelofibrosis (MF) Treatment Market, By Type 2019-2031 (USD Million)
52. China Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
53. China Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
54. India Myelofibrosis (MF) Treatment Market, By Type 2019-2031 (USD Million)
55. India Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
56. India Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
57. South America Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
58. South America Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
59. South America Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
60. Brazil Myelofibrosis (MF) Treatment Market, By Type 2019-2031 (USD Million)
61. Brazil Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
62. Brazil Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
63. Middle East and Africa Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
64. Middle East and Africa Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
65. Middle East and Africa Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
66. UAE Myelofibrosis (MF) Treatment Market, By Type, 2019-2031 (USD Million)
67. UAE Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
68. UAE Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
69. South Africa Myelofibrosis (MF) Treatment Market, By Type 2019-2031 (USD Million)
70. South Africa Myelofibrosis (MF) Treatment Market, By Route of Administration, 2019-2031 (USD Million)
71. South Africa Myelofibrosis (MF) Treatment Market, By End-Use, 2019-2031 (USD Million)
List of Figures
1. Global Myelofibrosis (MF) Treatment Market Segmentation
2. Myelofibrosis (MF) Treatment Market: Research Methodology
3. Market Size Estimation Methodology: Bottom-Up Approach
4. Market Size Estimation Methodology: Top-Down Approach
5. Data Triangulation
6. Porter’s Five Forces Analysis
7. Value Chain Analysis
8. Global Myelofibrosis (MF) Treatment Market Attractiveness Analysis by Type
9. Global Myelofibrosis (MF) Treatment Market Attractiveness Analysis by Route of Administration
10. Global Myelofibrosis (MF) Treatment Market Attractiveness Analysis by End-Use
11. Global Myelofibrosis (MF) Treatment Market Attractiveness Analysis by Region
12. Global Myelofibrosis (MF) Treatment Market: Dynamics
13. Global Myelofibrosis (MF) Treatment Market Share by Type (2023 & 2031)
14. Global Myelofibrosis (MF) Treatment Market Share by Route of Administration (2023 & 2031)
15. Global Myelofibrosis (MF) Treatment Market Share by End-Use (2023 & 2031)
16. Global Myelofibrosis (MF) Treatment Market Share by Regions (2023 & 2031)
17. Global Myelofibrosis (MF) Treatment Market Share by Company (2022)
This study forecasts revenue at global, regional, and country levels from 2019 to 2031. The Brainy Insights has segmented the global Myelofibrosis (MF) Treatment market based on below mentioned segments:
Global Myelofibrosis (MF) Treatment Market Type:
Global Myelofibrosis (MF) Treatment Market Route of Administration:
Global Myelofibrosis (MF) Treatment Market End-Use
Global Myelofibrosis (MF) Treatment Market by Region:
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