The global induced pluripotent stem cell (iPSC) market was valued at USD 2.1 billion in 2023, growing at a CAGR of 9.6% from 2024 to 2033. The market is expected to reach USD 5.2 billion by 2033. Due to the growing need for vaccine production, higher expenditures in the industry, and an expanding application portfolio from ongoing research and development efforts, the iPSC market is expanding quickly. The induced pluripotent stem cell (iPSC) market is growing due to the active infrastructure development undertaken by public and private institutions to support iPSC research.
Cells taken from adult somatic tissues are called induced pluripotent stem cells (iPSCs), and the introduction of particular genes and agents reprograms them. Through this reprogramming process, the iPSCs can develop pluripotent characteristics akin to embryonic stem cells. With their ability to reprogram cells from the same individual,iPSCs offer a useful tool for illness modelling. Retroviruses are employed as vectors to transfer the genes and other components required for iPSC reprogramming. iPSCs are used in many domains, such as gene treatments, toxicity research, drug discovery and development, and disease modelling. They have demonstrated promise in treating several cancers, diabetes mellitus, and cardiovascular illnesses. Because human iPSCs, in particular, have genotypes specific to certain diseases, new therapeutic methods customised for each patient are made possible. As iPSCs closely mimic the genetic composition of their donors, they enable researchers to examine diseases in a more pertinent and customised way. It creates new opportunities for comprehending the workings of disease systems and creating tailored treatments. iPSCs have the power to transform the area of regenerative medicine and offer cutting-edge treatments for a wide range of illnesses.
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In August 2021, for an undisclosed sum, the US pharmaceutical company Catalent purchased RheinCell Therapeutics GmbH, a German business that developed human induced pluripotent stem cells (iPSCs). With this acquisition, Catalent can create more advanced cell therapies using iPSCs and increase its market share in the gene and cell therapy industries.
In August 2021, To support its research and development programme, clinical operations, and commercialization activities for off-the-shelf pluripotent stem cell-CAR-NK (Chimeric Antigen Receptor-Natural Killer) products, HebeCell Corp. successfully raised USD 53 million in funding.
In April 2022, Promising preclinical findings demonstrated the tumor-killing capacity of Editas Medicine, Inc.'s NK cell therapy derived from induced pluripotent stem cells (iPSCs). The in-vitro and in-vivo outcomes show how well this novel strategy targets and eradicates tumours.
Growing need to culture human iPSCs- Businesses and research organisations are working to create induced pluripotent stem cells (iPSCs) with as little chance of genetic abnormalities leading to cancerous transformation as possible. The necessity to develop human iPSCs without using animal cells is becoming increasingly apparent globally, and major efforts are being made to accomplish this goal. Attention is also paid to standardising the environment for cell culture and differentiation.
High cost- The high expenses involved in iPSC development and commercialisation continue to be a significant obstacle to their widespread use. Addressing the bottleneck of standardisation of differentiation methods is crucial. From the perspective of effectiveness and safety, the incomplete knowledge of epigenetic modifications during reprogramming is especially concerning. Players in the market should concentrate on improving methods for producing clinical-gradeiPSCs quickly and affordably. Collaborations between academics and industry could improve the uses of iPSC platforms. Although laws vary from place to region, the market would benefit from supportive laws and rules. Continuing efforts to bank stem cells may make getting iPSC lines for scientific investigations easier.
Increasing research funding- In recent years, there has been a significant increase in financing for stem cell research from both the public and corporate sectors. This has fueled advancements in induced pluripotent stem cells (iPSCs), broadening their applications and stimulating additional study. Budgets for stem cell research have increased dramatically in countries like China, Japan, and numerous European countries; special attention has been paid to the potential application of iPSC technology in developing personalised regenerative treatments. For instance, government funding for iPSC studies had increased during 2020, according to a 2022 statement from the U.K. Stem Cell Foundation. Nonprofits dedicated to stem cell research have also seen an increase in private donations; the California Institute for Regenerative Medicine said in late 2021 that the year's private contributions had topped $300 million.
The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America emerged as the most significant global induced pluripotent stem cell (iPSC) market, with a 36.7% market revenue share in 2023.
The region benefits from the significant financing that government and private sectors give to research institutions and the strong presence of important industry companies. Furthermore, North America has a strong infrastructure for application and research fields like toxicity screening and tissue engineering, which supports market expansion. Furthermore, research involving induced pluripotent stem cells (iPSCs) is supported by organisations such as the National Institute of Health (NIH), the California Institute for Regenerative Medicine (CIRM), the National Institute of Neurological Disorders and Stroke (NINDS), and many others.
North America Region Induced Pluripotent Stem Cell (iPSC) Market Share in 2023 - 36.7%
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The derived cell segment is divided into fibroblasts, cardiomyocytes, hepatocytes, amniotic cells, and others. The cardiomyocytes segment dominated the market, with a market share of around 29% in 2023. As the company uses human-derived iPSCs, researchers can benefit from a steady supply of cardiomyocytes with a common genetic background for various investigations. This market sector is growing because of the increased utility of these cells in applications, including electrophysiology and metabolism studies.
The application segment is divided into academic research, toxicity screening, manufacturing, drug development & discovery, and regenerative medicine. The drug development & discovery segment dominated the market, with a market share of around 25% in 2023. The segment's growth is driven by major pharmaceutical companies' great interest in gaining iPSC knowledge due to its inherent benefits and prospective income streams.
Report Description:
Attribute | Description |
---|---|
Market Size | Revenue (USD Billion) |
Market size value in 2023 | USD 2.1 Billion |
Market size value in 2033 | USD 5.2 Billion |
CAGR (2024 to 2033) | 9.6% |
Historical data | 2020-2022 |
Base Year | 2023 |
Forecast | 2024-2033 |
Region | The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East & Africa. Furthermore, the regions are further analyzed at the country level. |
Segments | Derived Cell, Application |
As per The Brainy Insights, the size of the induced pluripotent stem cell (iPSC) market was valued at USD 2.1 billion in 2023 to USD 5.2 billion by 2033.
The global induced pluripotent stem cell (iPSC) market is growing at a CAGR of 9.6% during the forecast period 2024-2033.
North America emerged as the largest induced pluripotent stem cell (iPSC) market.
This study forecasts global, regional, and country revenue from 2020 to 2033. The Brainy Insights has segmented the global induced pluripotent stem cell (iPSC) market based on the below-mentioned segments:
Global Induced Pluripotent Stem Cell (iPSC) Market By Derived Cell:
Global Induced Pluripotent Stem Cell (iPSC) Market By Application:
Global Induced Pluripotent Stem Cell (iPSC) Market By Region:
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