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The global cardiotoxicity screening market is expected to grow from USD 18.33 billion in 2022 to USD 34.75 billion by 2030, at a CAGR of 8.32% during the forecast period 2022-2030. The North American region is expected to dominate the market in 2022.
Cardiotoxicity screening is a process used for the evaluation of toxic chemicals which can cause damage to the heart. The damage can be caused to the heart muscles, which can affect the functioning of the heart. Further, a dysfunction in electrophysiology can also be caused due to presence of a toxic substance. The cardiotoxicity assessment is necessary for the initial stages of drug discovery. The process of cardiotoxicity screening is essential for reducing the number of toxic substances and thus increasing the efficacy of the drug. There are many cardioactive substances which are used in heart failure treatment. Cardiotoxicity can also arise from certain medications or treatments the patients underwent a few years ago. Cardiotoxicity screening is essential, especially during the formulation of drugs intended to cure heart diseases.
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In June 2022, a significant player, Axol Bioscience, announced that their ventricular cardiomyocytes derived from IPSC had completed the in-vitro CiPA test. The test has revealed that these cells can be used to measure the level of cardiotoxicity, and thus an efficient cardiac model can be found for the screening of drugs.
Drivers:
Increasing cases of cardiotoxicity: With rising cases of cardiotoxicity, there has been a high demand for screening of the compounds used in manufacturing drugs. Cardiotoxicity screenings have several potential advantages over conventional testing methods, including the fact that they are more efficient and safe to be conducted on drugs. The cases of adverse reactions to cardiac drugs have been increasing among patients with existing heart conditions. The incidence of cardiotoxicity is more common in patients who have suffered from cancer treatment or any cardiac surgery. Thus, the requirement for conducting efficient cardiotoxicity screening products and services is increasing. Cardiotoxicity makes it challenging for the heart to carry out everyday activities and pump blood in the body. Thus, cardiotoxicity leads to the prevalence of cardiomyopathy, which weakens the capability of the heart to pump blood.
Restraints:
Lack of skilled professionals– Cardiotoxicity screening is in high demand due to the significant prevalence of cardiotoxicity. Cardiotoxicity screening operations require qualified professionals with the necessary training. There is high demand for such professionals to increase the efficacy of cardiotoxicity screening. However, there is a lack of these skilled professionals for conducting cardiotoxicity screening. Thus, these factors are restraining market growth.
Opportunities:
Increasing prevalence of cardiovascular diseases - Cardiovascular diseases, particularly ischemic heart disease (IHD) and stroke, are the leading cause of death and disability worldwide. Total CVD cases nearly doubled from 271 million in 1990 to 523 million in 2019, and CVD deaths increased steadily from 12.1 million in 1990 to 18.6 million in 2019. Disability-adjusted life years (DALYs) and years of life lost have increased dramatically globally, with years lived with disability doubling from 17.7 million to 22.5 million. Cardiovascular illnesses continue to be the world's most significant cause of disease burden. Outside of high-income nations, the CVD burden continues to climb, and frighteningly, the age-standardized rate of CVD has begun to grow in certain places where it was previously dropping in high-income countries. Among the regions, North America, followed by Europe and the Asia Pacific, will gain tremendous market share due to the presence of numerous leading global manufacturers throughout the area, with companies increasing their manufacturing potential. The increasing obese population suffering from heart failure drives the North American market. Further, the increased awareness of therapies and the availability of favourable reimbursement policies have accelerated market growth. In the case of Asia-Pacific, the development of healthcare infrastructure and supporting initiatives by the government have led to the market's growth.
Challenges:
Stringent regulations for product approval - The imposition of strict rules regarding the approval of cardiotoxicity screening products such as assays, kits, systems and services, especially in developing economies. In many regions, cardiotoxicity screening companies face multiple product approval regulations. There are several policies that these companies have to follow when their product is in the pipeline. There is a lack of standardization in the policies governing the process of cardiotoxicity screening in different regions, which makes it even more difficult for companies to expand their business across geographies.
Regional segmentation analysis:
The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. The North American region emerged as the most significant global cardiotoxicity screening market, with a market revenue share of 36.05% in 2022. Given the presence of major industry players, there is a high growth rate of the cardiotoxicity screening market in the region. The North American market will be driven by the presence of advanced healthcare and research and development facilities infrastructure to support the cardiotoxicity screening market, availability of systems, kits and software, and high investments by end-user industries. The growing incidence of cardiovascular diseases in regional countries has increased the frequency of cardiotoxicity screening. The Asia-Pacific region is anticipated to grow lucratively during the forecast period. The region has a high percentage of the population suffering from a chronic heart disorder, and the number of inflammation diseases is also increasing rapidly.
North America region Cardiotoxicity Screening Market Share in 2022 - 36.05%
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Technology Segment Analysis
The technology segment is divided into classic hERG safety assay, arrhythmogenic liability screening, QT prolongation assay, comprehensive in vitro proarrhytmia assay and others. The classic hERG safety assay segment dominated the market with a revenue share of around 35.11% in 2022. Classic hERG safety assay identifies the toxic compounds in the drug composition. These assays specifically test the effect of test compounds.
Product Segment Analysis
The product segment is divided into analyzers and instruments, reagents and kits and software and services. The analyzers and instruments segment dominated the market with a market share of 41.05% in 2022. Analyzers and instruments are required to carry out the cardiotoxicity screening process with utmost efficacy. Many instruments are used to separate the toxic components from the drug composition.
End-user Segment Analysis
The end-user segment includes pharmaceutical and biotechnology companies, academic and research institutes, contract research organizations and others. The pharmaceutical and biotechnology company segment dominated the market with a revenue share of around 45.22% in 2022. Pharmaceutical and biotech companies have a higher demand for cardiotoxicity screening due to its requirement in the drug discovery process. The drugs used in cardiac diseases should be free from toxic compounds. Thus, pharmaceutical and biotech companies invest in screening to pass the quality test.
Report Description:
| Attribute | Description |
|---|---|
| Market Size | Revenue (USD Billion) |
| Market size value in 2022 | USD 18.33 Billion |
| Market size value in 2030 | USD 34.75 Billion |
| CAGR (2022 to 2030) | 8.32% |
| Historical data | 2019-2020 |
| Base Year | 2021 |
| Forecast | 2022-2030 |
| Segments | The regions examined for the market are Europe, Asia Pacific, North America, South America, and Middle East & Africa. |
| Regional Segments | The research segment is based on technology, product, and end-user. |
As per The Brainy Insights, the size of the cardiotoxicity screening market was valued 18.33 billion in 2022 to USD 34.75 billion by 2030.
Global cardiotoxicity screening market is growing at a CAGR of 8.32% during the forecast period 2022-2030.
North America region emerged as the largest market for the cardiotoxicity screening.
The market's growth will be influenced by the growing prevalence of cardiovascular diseases.
The lack of skilled labour could hamper the market growth.
The increasing research and development for drug discovery process is providing huge opportunities to the market.
Key players are Admescope Ltd, Cyprotex, Stemina Biomarker Discovery, Eurofins Discovery, Molecular Devices, Axol Bioscience Ltd, AMRI Global, GVK Biosciences, Anbiqi Biotechnology, WuXi AppTec among others.
1. Introduction
1.1. Objective of the Study
1.2. Market Definition
1.3. Research Scope
1.4. Currency
1.5. Key Target Audience
2. Research Methodology and Assumptions
3. Executive Summary
4. Premium Insights
4.1. Porter’s Five Forces Analysis
4.2. Value Chain Analysis
4.3. Top Investment Pockets
4.3.1. Market Attractiveness Analysis By Technology
4.3.2. Market Attractiveness Analysis By Product
4.3.3. Market Attractiveness Analysis By End-user
4.3.4. Market Attractiveness Analysis By Region
4.4. Industry Trends
5. Market Dynamics
5.1. Market Evaluation
5.2. Drivers
5.2.1. Increasing demand for screening of cardiotoxicity substances
5.3. Restraints
5.3.1. Lack of skilled professionals
5.4. Opportunities
5.4.1. Increasing technological advancements in diseases diagnostics
5.5. Challenges
5.5.1. Regulations regarding product approval
6. Global Cardiotoxicity Screening Market Analysis and Forecast, By Technology
6.1. Segment Overview
6.2. Classic hERG Safety Assay
6.3. Arrhythmogenic Liability Screening
6.4. QT Prolongation Assay
6.5. Comprehensive in Vitro Proarrhytmia Assay
6.6. Others
7. Global Cardiotoxicity Screening Market Analysis and Forecast, By Product
7.1. Segment Overview
7.2. Analyzers and Instruments
7.3. Reagents and Kits
7.4. Software and Services
8. Global Cardiotoxicity Screening Market Analysis and Forecast, By End-user
8.1. Segment Overview
8.2. Pharmaceutical and Biotechnology Company
8.3. Academic and Research Institutes
8.4. Contact Research Organizations
8.5. Others
9. Global Cardiotoxicity Screening Market Analysis and Forecast, By Regional Analysis
9.1. Segment Overview
9.2. North America
9.2.1. U.S.
9.2.2. Canada
9.2.3. Mexico
9.3. Europe
9.3.1. Germany
9.3.2. France
9.3.3. U.K.
9.3.4. Italy
9.3.5. Spain
9.4. Asia-Pacific
9.4.1. Japan
9.4.2. China
9.4.3. India
9.5. South America
9.5.1. Brazil
9.6. Middle East and Africa
9.6.1. UAE
9.6.2. South Africa
10. Global Cardiotoxicity Screening Market-Competitive Landscape
10.1. Overview
10.2. Market Share of Key Players in the Cardiotoxicity Screening Market
10.2.1. Global Company Market Share
10.2.2. North America Company Market Share
10.2.3. Europe Company Market Share
10.2.4. APAC Company Market Share
10.3. Competitive Situations and Trends
10.3.1. Product Launches and Developments
10.3.2. Partnerships, Collaborations, and Agreements
10.3.3. Mergers & Acquisitions
10.3.4. Expansions
11. Company Profiles
11.1. Admescope Ltd
11.1.1. Business Overview
11.1.2. Company Snapshot
11.1.3. Company Market Share Analysis
11.1.4. Company Product Portfolio
11.1.5. Recent Developments
11.1.6. SWOT Analysis
11.2. Cyprotex
11.2.1. Business Overview
11.2.2. Company Snapshot
11.2.3. Company Market Share Analysis
11.2.4. Company Product Portfolio
11.2.5. Recent Developments
11.2.6. SWOT Analysis
11.3. Stemina Biomarker Discovery
11.3.1. Business Overview
11.3.2. Company Snapshot
11.3.3. Company Market Share Analysis
11.3.4. Company Product Portfolio
11.3.5. Recent Developments
11.3.6. SWOT Analysis
11.4. Eurofins Discovery
11.4.1. Business Overview
11.4.2. Company Snapshot
11.4.3. Company Market Share Analysis
11.4.4. Company Product Portfolio
11.4.5. Recent Developments
11.4.6. SWOT Analysis
11.5. Molecular Devices
11.5.1. Business Overview
11.5.2. Company Snapshot
11.5.3. Company Market Share Analysis
11.5.4. Company Product Portfolio
11.5.5. Recent Developments
11.5.6. SWOT Analysis
11.6. Axol Bioscience Ltd
11.6.1. Business Overview
11.6.2. Company Snapshot
11.6.3. Company Market Share Analysis
11.6.4. Company Product Portfolio
11.6.5. Recent Developments
11.6.6. SWOT Analysis
11.7. AMRI Global
11.7.1. Business Overview
11.7.2. Company Snapshot
11.7.3. Company Market Share Analysis
11.7.4. Company Product Portfolio
11.7.5. Recent Developments
11.7.6. SWOT Analysis
11.8. GVK Biosciences
11.8.1. Business Overview
11.8.2. Company Snapshot
11.8.3. Company Market Share Analysis
11.8.4. Company Product Portfolio
11.8.5. Recent Developments
11.8.6. SWOT Analysis
11.9. Anbiqi Biotechnology
11.9.1. Business Overview
11.9.2. Company Snapshot
11.9.3. Company Market Share Analysis
11.9.4. Company Product Portfolio
11.9.5. Recent Developments
11.9.6. SWOT Analysis
11.10. WuXi AppTec
11.10.1. Business Overview
11.10.2. Company Snapshot
11.10.3. Company Market Share Analysis
11.10.4. Company Product Portfolio
11.10.5. Recent Developments
11.10.6. SWOT Analysis
List of Table
1. Global Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
2. Global Classic hERG Safety Assay, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
3. Global Arrhythmogenic Liability Screening, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
4. Global QT Prolongation Assay, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
5. Global Comprehensive in Vitro Proarrhytmia Assay, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
6. Global Others, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
7. Global Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
8. Global Analyzers and Instruments, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
9. Global Reagents and Kits, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
10. Global Software and Services, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
11. Global Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
12. Global Pharmaceutical and Biotechnology Company, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
13. Global Academic and Research Institutes, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
14. Global Contact Research Organizations, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
15. Global Others, Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
16. Global Cardiotoxicity Screening Market, By Region, 2019-2030 (USD Billion)
17. North America Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
18. North America Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
19. North America Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
20. U.S. Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
21. U.S. Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
22. U.S. Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
23. Canada Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
24. Canada Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
25. Canada Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
26. Mexico Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
27. Mexico Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
28. Mexico Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
29. Europe Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
30. Europe Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
31. Europe Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
32. Germany Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
33. Germany Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
34. Germany Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
35. France Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
36. France Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
37. France Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
38. U.K. Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
39. U.K. Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
40. U.K. Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
41. Italy Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
42. Italy Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
43. Italy Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
44. Spain Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
45. Spain Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
46. Spain Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
47. Asia Pacific Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
48. Asia Pacific Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
49. Asia Pacific Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
50. Japan Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
51. Japan Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
52. Japan Cardiotoxicity Screening Market, By End-user 2019-2030 (USD Billion)
53. China Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
54. China Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
55. China Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
56. India Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
57. India Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
58. India Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
59. South America Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
60. South America Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
61. South America Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
62. Brazil Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
63. Brazil Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
64. Brazil Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
65. Middle East and Africa Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
66. Middle East and Africa Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
67. Middle East and Africa Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
68. UAE Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
69. UAE Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
70. UAE Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
71. South Africa Cardiotoxicity Screening Market, By Technology, 2019-2030 (USD Billion)
72. South Africa Cardiotoxicity Screening Market, By Product, 2019-2030 (USD Billion)
73. South Africa Cardiotoxicity Screening Market, By End-user, 2019-2030 (USD Billion)
List of Figures
1. Global Cardiotoxicity Screening Market Segmentation
2. Cardiotoxicity Screening Market: Research Methodology
3. Market Size Estimation Methodology: Bottom-Up Approach
4. Market Size Estimation Methodology: Top-Down Approach
5. Data Triangulation
6. Porter’s Five Forces Analysis
7. Value Chain Analysis
8. Global Cardiotoxicity Screening Market Attractiveness Analysis By Technology
9. Global Cardiotoxicity Screening Market Attractiveness Analysis By Product
10. Global Cardiotoxicity Screening Market Attractiveness Analysis By End-user
11. Global Cardiotoxicity Screening Market Attractiveness Analysis By Region
12. Global Cardiotoxicity Screening Market: Dynamics
13. Global Cardiotoxicity Screening Market Share by Technology (2022 & 2030)
14. Global Cardiotoxicity Screening Market Share by Product (2022 & 2030)
15. Global Cardiotoxicity Screening Market Share by End-user (2022 & 2030)
16. Global Cardiotoxicity Screening Market Share by Regions (2022 & 2030)
17. Global Cardiotoxicity Screening Market Share by Company (2021)
This study forecasts revenue at global, regional, and country levels from 2019 to 2030. The Brainy Insights has segmented the global cardiotoxicity screening market based on below mentioned segments:
Global Cardiotoxicity Screening Market by Technology:
Global Cardiotoxicity Screening Market by Product:
Global Cardiotoxicity Screening Market by End-user:
Global Cardiotoxicity Screening Market by Region:
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