Alexipharmic Drugs Market

Alexipharmic Drugs Market Size by Application (Alcoholic Overdose, Opioid Overdose, Benzodiazepine Overdose, Benzodiazepine Overdose, and Others), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies and Others), Regions, Global Industry Analysis, Share, Growth, Trends, and Forecast 2024 to 2033

Base Year: 2023 Historical Data: 2020-22
  • Report ID: TBI-14072
  • Published Date: Feb, 2024
  • Pages: 237
  • Category: Healthcare
  • Format: PDF
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The global alexipharmic drugs market was valued at USD 3 billion in 2023 and grew at a CAGR of 4% from 2024 to 2033. The market is expected to reach USD 4.44 billion by 2033. The rising cases of opioid overdose will drive the growth of the global alexipharmic drugs market.

Market Introduction:

Alexipharmics or alexipharmic drugs refer to substances counteracting poisons. They are more commonly known as "antidotes." the demand for antidotes is driven by the need to treat specific poisonings or toxic exposures. Antidotes are crucial in emergency medicine and toxicology, where they play a vital role in mitigating the harmful effects of various toxins. The prevalence of specific toxins, accidental poisonings, drug overdoses, and environmental exposures are driving the demand for alexipharmic drugs.

Alexipharmic Drugs Market Size

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Recent Development
  • Rising Pharmaceuticals, a subsidiary of Rising Pharma Holdings Inc., declared the approval, introduction, and instant commercial availability of Edetate calcium disodium injection. This launch will address the significant commercial shortage of this crucial medication in the US.  Rising's edetate calcium disodium injection is recommended for lowering blood lead levels and depot storage in cases of acute and chronic lead poisoning, as well as lead encephalopathy in adults and children.

Market Dynamics:

Drivers

The increasing instances of poisoning and overdose – The opioid epidemic has led to an increased need for antidotes to counteract opioid overdoses. Accidental or intentional chemical exposures contribute to a demand for antidotes. Instances of poisoning, especially in children, to address accidental ingestions of harmful substances increase the demand for alexipharmic drugs. The increasing awareness of the importance of timely poisoning treatment, driven by public health campaigns and educational initiatives spearheaded by regulatory authorities, contributes to an increased demand for antidotes.

Restraints:

The adverse reactions of alexipharmic drugs adverse reactions including allergic responses such as skin rashes or anaphylaxis, cardiovascular impacts, gastrointestinal symptoms like nausea or vomiting, and neurological effects ranging from dizziness to seizures will limit the market’s growth.  Additionally, antidotes may lead to respiratory distress, haematological complications, or local irritation at injection sites.

Opportunities:

Product innovations – Ongoing research in toxicology, supported by advancements in genomic and proteomic technologies, leads to a deeper understanding of toxins and their mechanisms of action, which leads to product innovations. Exploring innovative delivery mechanisms, such as nanotechnology, enhances the speed and precision of antidote deployment, furthering the alexipharmic drugs market. Regulatory requirements prompt pharmaceutical companies to invest in research and development efforts that align with emerging health priorities, fostering innovation. Collaborations among research institutes, industry players and government entities further amplify the market’s growth and development.

  • The death cap mushroom, Amanita phalloides, has long been known as the "killer of kings," yet it may be losing its power. Researchers may have discovered a counteragent for the lethal mushroom's venom.  When scientists discovered a possible remedy lately, they also focused on the human biochemical route required for the toxin from the mushrooms, known as α-amanitin, to enter cells. Indocyanine green, the molecule acting as an antidote, blocks that pathway. The researchers in Nature Communications published these results.
Regional segmentation analysis:

The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America emerged as the most significant global alexipharmic drugs market, with a 35% market revenue share in 2023.

The opioid epidemic, especially in the United States of America, is a significant driver, necessitating the widespread availability of alexipharmic drugs. Environmental hazards, industrial activities, and the potential for chemical exposures in North America amplify the need for alexipharmic drugs to manage and mitigate health risks arising from such incidents. Awareness, education campaigns, and regulatory changes increase demand for alexipharmic drugs. Advancements in pharmaceutical research also contribute to the market’s growth.

North America Region Alexipharmic Drugs Market Share in 2023 - 35%

 

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  • As the United States struggles to contain the rising number of victims from the fentanyl crisis, a new law will mandate that the Pentagon begin gathering data on overdoses among the ranks in 2024 and provide troops with an antidote for opioid overdoses.  After the yearly defence policy bill was passed last month, the Defence Department will now be required to keep records on substances used in overdoses, whether overdoses also involved doctor-prescribed drugs, and the number of overdoses classified as intentional or accidental.
Application Segment Analysis

The application segment is divided into alcoholic overdose, opioid overdose, benzodiazepine overdose, benzodiazepine overdose, and others. The opioid overdose segment dominated the market, with a market share of around 39% in 2023. The escalating opioid epidemic has led to a critical increase in opioid overdose cases, making alexipharmic drugs crucial in addressing this public health crisis. The overprescribing of opioids, the rise in illicit drug use, polydrug use, the lack of accessible addiction treatment options, the availability of potent opioids like fentanyl, and delayed medical responses in non-medical settings have all contributed to increasing demand for alexipharmic drugs for opioid overdose.

  • A nasal spray drug that is promoted as an additional means of counteracting overdoses brought on by synthetic opioids, such as fentanyl, which kills tens of thousands of Americans annually, was approved by the Food and Drug Administration. Opvee, a spray form of nalmefene, is marketed by drugmaker Indivior as a powerful drug that can prevent overdoses for hours and reverse overdoses rapidly, potentially saving lives. Opvee enters the expanding market for drugs that reverse overdose at a pivotal point in the country's drug issue.
Distribution Channel Segment Analysis

The distribution channel segment is divided into hospital pharmacies, retail pharmacies, online pharmacies and others. The hospital pharmacies segment dominated, with a market share of around 42% in 2023. hospital pharmacists ensure the safe and effective dispensing of antidotes, given their staff's expertise. Hospital pharmacies adhere to strict storage and handling guidelines, ensuring the stability and reliability of antidotes during emergencies, which fosters trust in consumers. Hospital pharmacies are preferred for purchasing antidotes due to their expertise, regulatory adherence, collaborative approach to patient care, and commitment to ensuring the availability of critical medications in emergencies within the hospital setting.

  • Retail stores and internet retailers will carry the first over-the-counter naloxone—a medication used to counteract opiate overdose—in stock.  The medication's manufacturer, Emergent BioSolutions, stated in a news release that the suggested retail price for the Narcan brand is $44.99 for a carton containing two doses. Initially, Walgreens, Rite Aid, Walmart, and CVS are among the shops that will sell it in-person and online. In March, the US Food and Drug Administration authorized Narcan for over-the-counter use in response to a record number of deaths from opioid overdoses, which are primarily caused by potent synthetic narcotics like fentanyl. Naloxone can be overdosed and revived in minutes with Narcan, a nasal spray version of the drug.
Some of the Key Market Players:
  • Alkermes, Inc.
  • B. Braun Melsungen AG
  • Bausch Health Companies Inc.
  • Emergent BioSolutions
  • Ethypharm S. A.
  • Fresenius SE & Co. KGaA
  • Hikma Pharmaceuticals
  • Merck & Co., Inc.
  • Mylan N.V.
  • SGPharma Pvt. Ltd.

Report Description:

Attribute Description
Market Size Revenue (USD Billion)
Market size value in 2023 USD 3 Billion
Market size value in 2033 USD 4.44 Billion
CAGR (2024 to 2033) 4%
Historical data 2020-2022
Base Year 2023
Forecast 2024-2033
Region The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East and Africa. Furthermore, the regions are further analyzed at the country level.
Segments Application and Distribution Channel

Frequesntly Asked Questions

As per The Brainy Insights, the size of the global alexipharmic drugs market was valued at USD 3 billion in 2023 to USD 4.44 billion by 2033.

Global alexipharmic drugs market is growing at a CAGR of 4% during the forecast period 2024-2033.

The market's growth will be influenced by the increasing instances of poisoning and overdose.

The adverse reactions of alexipharmic drugs could hamper the market growth.

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This study forecasts revenue at global, regional, and country levels from 2020 to 2033. The Brainy Insights has segmented the global alexipharmic drugs market based on below mentioned segments:

Global Alexipharmic Drugs Market by Application:

  • Alcoholic Overdose
  • Opioid Overdose
  • Benzodiazepine Overdose
  • Benzodiazepine Overdose
  • Others

Global Alexipharmic Drugs Market by Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
  • Others

Global Alexipharmic Drugs Market by Region:

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
  • Asia-Pacific
    • Japan
    • China
    • India
  • South America
    • Brazil
  • Middle East and Africa  
    • UAE
    • South Africa

Methodology

Research has its special purpose to undertake marketing efficiently. In this competitive scenario, businesses need information across all industry verticals; the information about customer wants, market demand, competition, industry trends, distribution channels etc. This information needs to be updated regularly because businesses operate in a dynamic environment. Our organization, The Brainy Insights incorporates scientific and systematic research procedures in order to get proper market insights and industry analysis for overall business success. The analysis consists of studying the market from a miniscule level wherein we implement statistical tools which helps us in examining the data with accuracy and precision. 

Our research reports feature both; quantitative and qualitative aspects for any market. Qualitative information for any market research process are fundamental because they reveal the customer needs and wants, usage and consumption for any product/service related to a specific industry. This in turn aids the marketers/investors in knowing certain perceptions of the customers. Qualitative research can enlighten about the different product concepts and designs along with unique service offering that in turn, helps define marketing problems and generate opportunities. On the other hand, quantitative research engages with the data collection process through interviews, e-mail interactions, surveys and pilot studies. Quantitative aspects for the market research are useful to validate the hypotheses generated during qualitative research method, explore empirical patterns in the data with the help of statistical tools, and finally make the market estimations.

The Brainy Insights offers comprehensive research and analysis, based on a wide assortment of factual insights gained through interviews with CXOs and global experts and secondary data from reliable sources. Our analysts and industry specialist assume vital roles in building up statistical tools and analysis models, which are used to analyse the data and arrive at accurate insights with exceedingly informative research discoveries. The data provided by our organization have proven precious to a diverse range of companies, facilitating them to address issues such as determining which products/services are the most appealing, whether or not customers use the product in the manner anticipated, the purchasing intentions of the market and many others.

Our research methodology encompasses an idyllic combination of primary and secondary initiatives. Key phases involved in this process are listed below:

MARKET RESEARCH PROCESS

Data Procurement:

The phase involves the gathering and collecting of market data and its related information with the help of different sources & research procedures.

The data procurement stage involves in data gathering and collecting through various data sources.

This stage involves in extensive research. These data sources includes:

Purchased Database: Purchased databases play a crucial role in estimating the market sizes irrespective of the domain. Our purchased database includes:

  • The organizational databases such as D&B Hoovers, and Bloomberg that helps us to identify the competitive scenario of the key market players/organizations along with the financial information.
  • Industry/Market databases such as Statista, and Factiva provides market/industry insights and deduce certain formulations. 
  • We also have contractual agreements with various reputed data providers and third party vendors who provide information which are not limited to:
    • Import & Export Data
    • Business Trade Information
    • Usage rates of a particular product/service on certain demographics mainly focusing on the unmet prerequisites

Primary Research: The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. Primary research mainly involves in telephonic interviews, E-mail interactions and face-to-face interviews with the raw material providers, manufacturers/producers, distributors, & independent consultants. The interviews that we conduct provides valuable data on market size and industry growth trends prevailing in the market. Our organization also conducts surveys with the various industry experts in order to gain overall insights of the industry/market. For instance, in healthcare industry we conduct surveys with the pharmacists, doctors, surgeons and nurses in order to gain insights and key information of a medical product/device/equipment which the customers are going to usage. Surveys are conducted in the form of questionnaire designed by our own analyst team. Surveys plays an important role in primary research because surveys helps us to identify the key target audiences of the market. Additionally, surveys helps to identify the key target audience engaged with the market. Our survey team conducts the survey by targeting the key audience, thus gaining insights from them. Based on the perspectives of the customers, this information is utilized to formulate market strategies. Moreover, market surveys helps us to understand the current competitive situation of the industry. To be precise, our survey process typically involve with the 360 analysis of the market. This analytical process begins by identifying the prospective customers for a product or service related to the market/industry to obtain data on how a product/service could fit into customers’ lives.

Secondary Research: The secondary data sources includes information published by the on-profit organizations such as World bank, WHO, company fillings, investor presentations, annual reports, national government documents, statistical databases, blogs, articles, white papers and others. From the annual report, we analyse a company’s revenue to understand the key segment and market share of that organization in a particular region. We analyse the company websites and adopt the product mapping technique which is important for deriving the segment revenue. In the product mapping method, we select and categorize the products offered by the companies catering to domain specific market, deduce the product revenue for each of the companies so as to get overall estimation of the market size. We also source data and analyses trends based on information received from supply side and demand side intermediaries in the value chain. The supply side denotes the data gathered from supplier, distributor, wholesaler and the demand side illustrates the data gathered from the end customers for respective market domain.

The supply side for a domain specific market is analysed by:

  • Estimating and projecting penetration rates through analysing product attributes, availability of internal and external substitutes, followed by pricing analysis of the product.
  • Experiential assessment of year-on-year sales of the product by conducting interviews.

The demand side for the market is estimated through:

  • Evaluating the penetration level and usage rates of the product.
  • Referring to the historical data to determine the growth rate and evaluate the industry trends

In-house Library: Apart from these third-party sources, we have our in-house library of qualitative and quantitative information. Our in-house database includes market data for various industry and domains. These data are updated on regular basis as per the changing market scenario. Our library includes, historic databases, internal audit reports and archives.

Sometimes there are instances where there is no metadata or raw data available for any domain specific market. For those cases, we use our expertise to forecast and estimate the market size in order to generate comprehensive data sets. Our analyst team adopt a robust research technique in order to produce the estimates:

  • Applying demographic along with psychographic segmentation for market evaluation
  • Determining the Micro and Macro-economic indicators for each region 
  • Examining the industry indicators prevailing in the market. 

Data Synthesis: This stage involves the analysis & mapping of all the information obtained from the previous step. It also involves in scrutinizing the data for any discrepancy observed while data gathering related to the market. The data is collected with consideration to the heterogeneity of sources. Robust scientific techniques are in place for synthesizing disparate data sets and provide the essential contextual information that can orient market strategies. The Brainy Insights has extensive experience in data synthesis where the data passes through various stages:

  • Data Screening: Data screening is the process of scrutinising data/information collected from primary research for errors and amending those collected data before data integration method. The screening involves in examining raw data, identifying errors and dealing with missing data. The purpose of the data screening is to ensure data is correctly entered or not. The Brainy Insights employs objective and systematic data screening grades involving repeated cycles of quality checks, screening and suspect analysis.
  • Data Integration: Integrating multiple data streams is necessary to produce research studies that provide in-depth picture to the clients. These data streams come from multiple research studies and our in house database. After screening of the data, our analysts conduct creative integration of data sets, optimizing connections between integrated surveys and syndicated data sources. There are mainly 2 research approaches that we follow in order to integrate our data; top down approach and bottom up approach.

Market Deduction & Formulation: The final stage comprises of assigning data points at appropriate market spaces so as to deduce feasible conclusions. Analyst perspective & subject matter expert based holistic form of market sizing coupled with industry analysis also plays a crucial role in this stage.

This stage involves in finalization of the market size and numbers that we have collected from data integration step. With data interpolation, it is made sure that there is no gap in the market data. Successful trend analysis is done by our analysts using extrapolation techniques, which provide the best possible forecasts for the market.

Data Validation & Market Feedback: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helps us finalize data-points to be used for final calculations.

The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. The data validation interview and discussion panels are typically composed of the most experienced industry members. The participants include, however, are not limited to:

  • CXOs and VPs of leading companies’ specific to sector
  • Purchasing managers, technical personnel, end-users
  • Key opinion leaders such as investment bankers, and industry consultants

Moreover, we always validate our data and findings through primary respondents from all the major regions we are working on.

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