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The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America emerged as the most significant global cancer gene therapy market, with a 44% market revenue share in 2023.
The region has sophisticated hospital and clinical experimental and research centres. They are capable of providing intricate treatments like gene therapies. This infrastructure supports cost efficient delivery of therapies such as the CAR T-cell treatments. The availability of such research infrastructure increases the pace at which technologies such as the CRISPR-based gene editing and Immune-based treatments are developed. Furthermore, the high chance of contracting cancer in North America increases the need for innovative therapeutic products, resulting in the demand for gene therapies. The region also receives considerable public/private finance for its anatomic and molecular growth and for clinical research.
North America Region Cancer Gene Therapy Market Share in 2023 - 44%
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The therapy type segment is divided into gene transfer therapy and gene editing therapy. The gene transfer therapy segment dominated the market, with a market share of around 57% in 2023. This therapy involves transferring of genetic material into a patient’s cells in order to replace damaged gene, correct a gene mutation or add new gene that can assist in combating cancer. Gene transfer therapies make use of viruses and they have been noted to have high transfer efficiency. Gene transfer therapies have become one of the leading treatments of cancer due to their proven efficacy for treating hematologic cancers such as leukaemia. This type of treatment is focused on attacking the particular cell and disease on its molecular level which is what makes it much more personal and can be considered more efficient compared to average treatment methods, such as chemotherapy or radiation. Importantly, CAR T-cell therapies – a form of gene transfer therapy – has gained an approval and success for the treatment of blood cancers thus transforming this field. These therapies have shown very high success rates in clinical trials, further increasing the occurrence and innovation of gene transfer-based therapies.
The cancer type segment is divided into leukaemia, lung cancer, breast cancer, and melanoma. The leukaemia segment dominated the market, with a market share of around 45% in 2023. Leukaemia takes over half of the market share in the cancer gene therapy due to the advances which have occurred in the gene treatment of cancers especially the hematologic malignancy. Cancer of the blood and bone marrow called leukaemia has attracted a lot of groundbreaking treatments, including cell-gene therapies such as CAR T-cell therapy. These therapies include altering a patient’s T-cells so that they may better identify and destroy leukaemia cells, which are very personalized and efficient. As to the reason why leukaemia dominates this market, the idea here is that immune cells can be easily harvested from the body and genetically engineered and administered back into the body compared to the challenges posed when dealing with gene delivery in solid tumour cells.
The delivery method segment is divided into viral vectors and non-viral vectors. The viral vectors segment dominated the market, with a market share of around 56% in 2023. Viral vectors have become the most widely used system for delivering genetic material in cancer gene therapy because of their high transduction efficiency. These vectors, usually virus derived, are designed to introduce therapeutic genes into cancer cells without eliciting disease symptoms which makes them ideal for gene transfer. The basic advantage of using viral vectors is the fact that viruses are created to penetrate and introduce genetic material into cells. This intrinsic characteristic is used to guarantee that the therapeutic genes get to the cancer cells and are incorporated into its genome in a bid to facilitate genetically engineered therapies for cancer. The ability of viral vectors to specifically home in on cancers cells and the ability of these vectors to transfer large genes makes them ideal for clinical and research gene therapy.
The end user segment is divided into hospitals, research institutes, and clinics. The hospitals segment dominated the market, with a market share of around 38% in 2023. Hospitals spearhead the global cancer gene therapy end-users’ market due to their overall responsibility when it comes to providing intricate and specialized therapies. Because gene therapies for cancer entails sophisticated strategies that need specialized equipment and human resource, and close monitoring of patients’ condition, it is usually administered in hospitals. Many of these approved therapies, especially those using cell-based treatments such as the CAR T-cell therapy, demands equipment and facilities for that are more common in hospital settings such as cell collectors, modifiers. The cancer gene therapies are also invasive, as much as the cancers they target, and require the coordinated input of oncologists, immunologists, geneticists and other personnel often found in hospitals. Furthermore, hospitals are more prepared in case of side effects or any other effects resulting from gene therapies when compared to other treatments because gene therapies are mostly new treatments or therapies.
This study forecasts revenue at global, regional, and country levels from 2020 to 2033. The Brainy Insights has segmented the global cancer gene therapy market based on below mentioned segments:
Global Cancer Gene Therapy Market by Therapy Type:
Global Cancer Gene Therapy Market by Cancer Type:
Global Cancer Gene Therapy Market by Delivery Method:
Global Cancer Gene Therapy Market by End User:
Global Cancer Gene Therapy Market by Region:
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